Ageing is a natural process, but modern nutritional science is uncovering ways to support healthy ageing at the cellular level. Through targeted supplementation, it's now possible to enhance energy, boost cognitive resilience, and maintain youthful skin and vitality well into later decades. Below, we explore seven of the most promising anti-ageing supplement ingredients, each backed by scientific research.
1. Nicotinamide Mononucleotide (NMN)
NMN is a precursor to NAD+ (nicotinamide adenine dinucleotide), a molecule vital for mitochondrial function, DNA repair and energy production. As NAD+ levels decline with age, NMN supplementation helps restore youthful cellular function, improve metabolism, and enhance physical endurance. Early human trials show encouraging results.
2. Coenzyme Q10 (CoQ10)
CoQ10 is an antioxidant found in nearly every cell of the body, essential for generating energy within mitochondria. Ageing, stress, and certain medications reduce CoQ10 levels. Supplementation can support heart health, reduce fatigue, and improve skin firmness and elasticity.
3. Pyrroloquinoline Quinone (PQQ)
PQQ works synergistically with CoQ10 to promote the growth of new mitochondria—a process called mitochondrial biogenesis. This not only increases cellular energy output but also enhances brain function, memory, and protection against cognitive decline.
4. Collagen
Collagen provides structural integrity to the skin, joints, and connective tissues. Its natural decline with age contributes to wrinkles, sagging, and joint discomfort. Supplementing with hydrolysed collagen peptides has been shown to improve skin hydration, elasticity, and reduce signs of ageing.
5. Turmeric (Curcumin)
Curcumin, the main active compound in turmeric, exhibits potent anti-inflammatory and antioxidant properties. It helps protect cells from oxidative damage, supports brain health, and reduces the risk of chronic age-related diseases. Bioavailability is improved when combined with black pepper extract (piperine).
6. Omega-3 Fatty Acids (EPA & DHA)
Omega-3s are essential fats that support cardiovascular, neurological, and skin health. EPA and DHA reduce inflammation, support brain ageing, and may improve mood and cognitive function. They also maintain the skin’s lipid barrier, aiding in moisture retention and reduced wrinkle formation.
7. Lingzhi (Reishi Mushroom)
Lingzhi, known as Reishi, is a revered medicinal mushroom used for centuries in East Asia. Its bioactive compounds—such as triterpenoids and polysaccharides—support immune function, reduce stress, and promote sleep. Its adaptogenic properties help the body cope with ageing-related stressors.
While ageing cannot be stopped, it can be influenced. These natural compounds offer promising support for those looking to maintain vitality, cognitive sharpness, and youthful appearance. For best results, integrate supplementation with a healthy lifestyle, balanced diet, stress management, and regular physical activity.
As always, consult a qualified health professional before beginning any new supplement protocol, especially if you are managing chronic health conditions or taking medication.